![neck diagrams. neck diagrams.](https://static.mercdn.net/item/detail/orig/photos/m74566774245_1.jpg)
No serious AEs occurred.Ĭompared with BTX-A, the HA compound filling plus mesotherapy combined treatment significantly improved moderate-to-severe horizontal neck lines and achieved a high level of patients’ satisfaction. Significantly higher pain ratings, higher incidence, and longer recovery of AEs (erythema, edema, and ecchymosis) were noticed in the combined treatment group (P<0.001). The GAIS and patients’ satisfaction ratings were significantly higher for the HA combined treatment group (P=0.000).
![neck diagrams. neck diagrams.](https://i.pinimg.com/originals/59/c2/71/59c271307fab0667f2b4c446378ccaca.jpg)
Cases of different baseline grades (2, 2.5, and 3) demonstrated similar outcomes. Compared with BTX-A, the HA compound filling plus mesotherapy combined treatment significantly improved the horizontal neck lines grades on all follow-up visits (P=0.000). Twenty-five patients received HA filling plus mesotherapy combined treatment and 23 received BTX-A injection. Improvement of the neck lines grades, global aesthetic improvement scale (GAIS), patient satisfaction, and adverse events (AEs) were evaluated and compared on 1, 3, 6, and 10 months after the final treatment. This multi-center, randomized, evaluator-blinded, prospective study enrolled female patients with moderate-to-severe horizontal neck lines corrected with either 2-3 sessions of non-cross-linked HA compound filling plus mesotherapy combined treatment or one session of BTX-A injection. The purpose of this study was to investigate the efficacy, safety, and subject satisfaction of non-cross-linked hyaluronic acid (HA) compound filling plus mesotherapy combined treatment for the correction of horizontal neck lines, in comparison with BTX-A. The hyaluronic acid filler, Restylane Refyne, achieved significant improvement in static horizontal neck rhytides using either a cannula or needle without any serious side effects, although the needle was more effective.Īlthough energy devices and botulinum toxin-A (BTX-A) could alleviate the age-related laxity, ptosis, and platysmal bands, they have limited efficacy on horizontal neck lines. In addition, the blind evaluator, subjects, and investigator rated the side of the neck injected with a needle as having significantly greater improvement than the cannula. Subjects were graded using the Transverse Neck Line Scale, Canfield photography, and the Global Aesthetic Improvement Scale.Ī significant improvement 30 days after the last treatment was achieved on the Transverse Neck Line Scale when comparing HARR with saline according to the blind evaluator, subjects, and investigator without any significant side effects. Twenty-six subjects were randomized to receive up to 1 mL of the HA filler Restylane Refyne (HARR, n = 20) or saline (n = 6) using a cannula on one side and a needle on the other with optional repeat treatment.
NECK DIAGRAMS. TRIAL
Hyaluronic acid (HA) fillers have been studied extensively on the face however, their safety and efficacy on the neck has not yet been evaluated in a prospective trial in the United States.Īnalyze the efficacy and safety of a HA filler for static horizontal neck rhytides using either a cannula or needle. This represents the state of the art on which to base further developments necessary for optimal and safe outcomes of treatment with the PLLA-based collagen stimulators and others in this class for body rejuvenation. Key features of the concerned zones and the main clinical signs affecting the body part as well as the injection modalities are provided along with the aesthetic results. The available published data, although still limited, are presented by body area, neck and chest, buttocks, abdomen, upper arms, thighs, knees, and hands. This review focuses on poly-L-lactic acid (PLLA), used in the first collagen stimulator and one of the most investigated in facial and in off-facial body applications.
![neck diagrams. neck diagrams.](http://poster.4teachers.org/imgFilePoster/207773.jpg)
NECK DIAGRAMS. SKIN
Their use is expanding and allows addressing various issues including volume loss, skin laxity, cellulite, striae distensae and wrinkles. In appropriate conditions of use, they are now used for body rejuvenation in clinical practice. Furthermore, they are associated with long-lasting efficiency, a high level of patient satisfaction and a good safety profile, with mainly minor adverse events reported. Different dermal fillers are available and include collagen stimulators initially developed to restore facial volume. Based on the beneficial outcomes of these treatments in many facial areas, a new trend is developing to target body areas. Soft-tissue dermal fillers can meet these expectations. Patients are looking for safe and effective minimally invasive aesthetic procedures. Requests for non-surgical body rejuvenation are increasing. The number of aesthetic procedures performed worldwide continues to grow together with an increase in the population seeking the restoration or preservation of a youthful appearance.